IMMUNOLOGICAL STUDIES IN BRONCHIAL ASTHMA
Keywords:
Bronchial Asthma, Immunology, Immunoglobulin, IgEAbstract
Immunology is the study of the body’s defence mechanism against disease. Immunoglobulins are proteins produced by plasma cells and lymphocytes and are characteristic of these cells. They play essential role in the body’s immune system by attaching to the foreign substance like bacteria. Bronchial asthma is a syndrome with a variety of disorders of the bronchi and is associated with the allergic hypersensitivity to certain allergens. Immunoglobulin E (IgE) is a class of immunoglobulin that includes the antibodies ellucited by an allergic substance (allergen). Asthma caused due to allergens was found to be more prevalent amongst males(65%) than in female (35%). The mean IgE values were significantly increased in the asthmatics, almost 20 times high value of IgE were observed as compared to healthy controls. Also high IgE levels were observed in males as compared to the females in the same age group. Both these findings are suggestive that IgE plays as important role in the detection and prevalence of allergic asthma.
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